Experimental Investigations into Sarcomas. Therapy Using Ferromagnetically Induced Cytostatics por Manfred Georg Krukemeyer

Experimental Investigations into Sarcomas. Therapy Using Ferromagnetically Induced Cytostatics por Manfred Georg Krukemeyer

Titulo del libro: Experimental Investigations into Sarcomas. Therapy Using Ferromagnetically Induced Cytostatics

Autor: Manfred Georg Krukemeyer

Número de páginas: 136 páginas

Fecha de lanzamiento: December 28, 2018

ISBN: 9783658205904

Editor: Springer Nature

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Manfred Georg Krukemeyer con Experimental Investigations into Sarcomas. Therapy Using Ferromagnetically Induced Cytostatics

<P>MANFRED GEORG KRUKEMEYER FIRST DESCRIBES MAGNETIC DRUG TARGETING, BY WHICH IS MEANT THE FOCUSED APPLICATION OF DRUGS, E.G. THE INTRODUCTION OF A CYTOSTATIC, AND WHICH IS AIMED AT OPTIMISING ITS LOCALLY THERAPEUTIC EFFECT. THE AUTHOR THUS ACHIEVES A HIGH CONCENTRATION OF CYTOSTATIC AT THE SITE OF THE TUMOUR. THE PARTICLES HAVE TO BE LARGE ENOUGH TO BE ATTRACTED BY A MAGNETIC FIELD AND SO FIND THEIR WAY INTO THE TUMOUR, WHERE THEY RELEASE THEIR ACTIVE INGREDIENT. THE AIM OF THE HYPOTHESIS FORMED BY ONE OF THE AUTHOR’S STUDY GROUPS WAS TO SHOW IN A SCIENTIFIC EXPERIMENT THAT IN THIS CASE CYTOSTATICS COUPLED WITH IRON PARTICLES [FE<SUB>3</SUB>O<SUB>4</SUB>] CAN BE INTRODUCED INTO A TUMOUR. THE FOCUSED INTRODUCTION OF DRUGS – MAGNETIC DRUG TARGETING – RESULTS IN FASTER ARRIVAL OF THE ACTIVE INGREDIENT AT THE TARGET SITE TOGETHER WITH A REDUCED QUANTITY OF ACTIVE SUBSTANCES. FOR THIS REASON MAGNETIC DRUG TARGETING IS ALSO INTERESTING FROM AN ECONOMIC POINT OF VIEW.</P>